To investigate the phenotype associated with estrogen receptor alpha (ER) expression in breast carcinoma, gene expression profiles of 58 node-negative breast carcinomas discordant for ER status were determined using DNA microarray technology. Using artificial neural networks as well as standard hierarchical clustering techniques, the tumors could be classified according to ER status, and a list of

This work adds a quantitative description of distortion to the structured design method of negative-feedback amplifiers. It constitutes a power-series representation of the feedback amplifier, which may include dynamic (memory) effects, where the design parameters appear explicitly. These results have been incorporated into the systematic design method. It now includes design steps for calculating

A method is described by which it is possible to measure fluence rate (scalar irradiance) using a cosine-sensitive instrument intended for measurement of irradiance (vector irradiance).

In this study, the IPFM model is extended to account for the presence of ectopic beats and heart rate turbulence (HRT). Based on the model extension, a new approach to characterize HRT is presented based on a set of Karhunen- Loeve (KL) basis functions. The three most significant basis functions possess attractive physiological interpretations which reflect the difference in heart rate prior to th

A study to determine and compare the sensitivities and specificities of the comparative cervical tuberculin (CCT) and gamma-interferon (IFN-gamma) tests for the diagnosis of bovine tuberculosis was conducted on 30 zebu oxen. The results of the tests were compared with the presence of acid-fast bacilli found by bacteriological culturing and histopathological examinations. The sensitivity and specif

We report 2 cases of severe infections due to Pasteurella multocida, both occurring during pregnancy in previously healthy women. Both women had contact with animals (dog and cat) but neither of them had been bitten. Apart from a slight decrease in IgG levels, no immunological defects could be detected. Both women had received oral phenoxymethylpenicillin in the early phase of the disease, but sti

This paper concerns propagation of transient electromagnetic waves in laterally discontinuous dispersive media. The approach, used here, employs a component decomposition of all fields. Specifically, the propagation operator that maps a transverse field on one plane to another plane is specified. Expansion of this mapping near the wave front determines the precursor or forerunner of the problem.

Obituary portrait of Dr h.c. Einar Hansen, Danishborn Swedish publisher and great donor to Lund University.

The exposure to Th-232 from TIG welding with thoriated electrodes has been determined at five different workshops. Welding with both alternating and direct current was investigated. The exposure levels of Th-232 were generally below 10 mBq m(-3) in the breathing zone of the welders. Two samples from AC welding showed significant higher exposure levels, probably due to maladjustment of the TIG weld

Background. The best mode of delivery in cases of intrauterine growth restriction (IUGR) with umbilical artery blood flow changes is not well elucidated. Objective. To evaluate outcome in IUGR with umbilical artery blood flow changes planned for vaginal delivery after a negative oxytocin challenge test (OCT). Methods. In 84 term singleton pregnancies with suspected IUGR and no unanimous indicati

Mutations in the gene encoding laminin (LM) alpha 2 chain cause congenital muscular dystrophy. Here, we show that extraocular muscle (EOM) is spared upon complete LM alpha 2 chain absence. The major LM chains in limb muscle basement membranes are alpha 2, beta 1, beta 2 and gamma 1 whereas alpha 2, alpha 4, beta 1, beta 2 and gamma 1 chains are expressed in EOM. Expression of LMoA chain mRNA is fu

Background: Previous studies of patients with type 2 diabetes showed that cinnamon lowers fasting serum glucose, triacylglycerol, and LDL- and total cholesterol concentrations. Objective: We aimed to study the effect of cinnamon on the rate of gastric emptying, the postprandial blood glucose response, and satiety in healthy subjects. Design: The gastric emptying rate (GER) was measured by using st