Crack paths in an elastic layer on top of a substrate are considered. Crack growth is initiated from an edge crack in the layer. The plane of the initially straight crack forms an angle to the free surface. The load consists of a pair of forces applied at the crack mouth and parallel to the interface. Crack paths are calculated using a boundary element method. Crack growth is assumed to proceed al

To ensure that listeners pay attention and do not habituate, emotionally intense vocalizations may be under evolutionary pressure to exploit processing biases in the auditory system by maximising their bottom-up salience. This “salience code” hypothesis was tested using 128 human nonverbal vocalizations representing eight emotions: amusement, anger, disgust, effort, fear, pain, pleasure, and sadne

Background. Secondary hyperparathyroidism (sHPT) is characterized by over function of the parathyroid glands and disturbances in mineral metabolism as a result of renal failure. It is common among patients with end-stage renal disease (ESRD) and it often persists after successful renal transplantation. sHPT is associated with osteoporosis and cardiovascular morbidity and mortality. There are two mBackground. Secondary hyperparathyroidism (sHPT) is characterized by over function of the parathyroid glands and disturbances in mineral metabolism as a result of renal failure. It is common among patients with end-stage renal disease (ESRD) and it often persists after successful renal transplantation. sHPT is associated with osteoporosis and cardiovascular morbidity and mortality. There are two m

Article 20 of the United Nations Convention on the Rights of the Childrecognises the vulnerability of children growing up outside a familyenvironment, and sets the ground for the paradigm of ‘institutions asa last resort’. However, ‘care homes’ or ‘hostels’ are still common formsof alternative care solutions for children from impoverished familiesin India. This article asks to what extent the clea

Urban densification, despite the economic and social opportunities it offers, brings with it challenges to the well-being of citizens. A direct effect of densification is the rise in noise- and vibration-producing sources, which can lead to both health and comfort issues. In determining the risk associated with excessive vibration levels, the distance between the source and the receiver or target

In the context of range-independent solid media, we propose a well-conditioned dynamic stiffness matrix for an elastic layer sitting over an elastic half-space. This formulation overcomes the well-known problem of numerical ill-conditioning when solving the system of equations for deep-layered strata. The methodology involves the exact solutions of transformed ordinary differential equations in th

To predict ground-borne vibration levels caused by railway traffic, models for estimating the load from the vibration source, as well as the vibration transmission through the ground, are needed. In the present paper, a finite element formulation in a frame of reference following the moving load, is used for modeling a railway slab track. The response of the underlying soil is represented through

Singleshot polychromatic coherent diffractive imaging is performed with a high-intensity high-order harmonic generation source. The coherence properties are analyzed and several reconstructions show the shot-to-shot fluctuations of the incident beam wavefront. The method is based on a multi-step approach. First, the spectrum is extracted from double-slit diffraction data. The spectrum is used as i

Artikeln beskriver två insamlare av folkloristiskt material som var verksamma kring sekelskiftet 1900. Här diskuteras hur det äldre uppteckningsmaterial som finns i arkiven har kommit till och den roll som insamlarna spelade för det som samlades in.

The role of auditory feedback in vocal production has mainly been investigated by altered auditory feedback (AAF) in real time. In response, speakers compensate by shifting their speech output in the opposite direction. Current theory suggests this is caused by a mismatch between expected and observed feedback. A methodological issue is the difficulty to fully isolate the speaker’s hearing so that

Energy-intensive industries (EIIs) produce basic materials that are responsible for around 22 percent of global CO2 emissions. The emissions keep increasing due to growing demand for basic materials as the world develops and effective global climate policy responses remain lacking. Reversing this trend and aligning the emissions trajectory with the goals of the Paris Agreement is an urgent and cha

Darwinian evolution of tumor cells remains underexplored in childhood cancer. We here reconstruct the evolutionary histories of 56 pediatric primary tumors, including 24 neuroblastomas, 24 Wilms tumors and 8 rhabdomyosarcomas. Whole genome copy number and whole exome mutational profiling of multiple regions per tumor was performed followed by clonal deconvolution to reconstruct a phylogenetic tree

Liquid biopsy allows assessment of multiple analytes, providing temporal information with potential for improving understanding of cancer evolution and clinical management of patients. Although liquid biopsies are intensely investigated for prediction and response monitoring, preanalytic variables are of primary concern for clinical implementation, including categories of collection method and sam