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Dynamic glucose enhanced imaging using direct water saturation

PURPOSE: Dynamic glucose enhanced (DGE) MRI studies employ CEST or spin lock (CESL) to study glucose uptake. Currently, these methods are hampered by low effect size and sensitivity to motion. To overcome this, we propose to utilize exchange-based linewidth (LW) broadening of the direct water saturation (DS) curve of the water saturation spectrum (Z-spectrum) during and after glucose infusion (DS-

A frequency domain analysis of slow coherency in networked systems

Network coherence generally refers to the emergence of simple aggregated dynamical behaviors, despite heterogeneity in the dynamics of the subsystems that constitute the network. In this paper, we develop a general frequency domain framework to analyze and quantify the level of network coherence that a system exhibits by relating coherence with a low-rank property of the system's input–output resp

A defossilised EU petrochemical production system : Consequences for the meta-cluster in the Antwerp-Rotterdam-Rhine-Ruhr Area

Today's petrochemical industry relies on fossil hydrocarbons, not only for energy purposes but also as feedstock. This use of fossil materials is being challenged by the European Union's target to achieve climate neutrality by 2050. The most affected region in Europe is the cross-border region between Antwerp, Rotterdam and the Rhine-Ruhr area in western Germany, an interconnected petrochemical me

Development of an All-Marine 3D Printed Bioactive Hydrogel Dressing for Treatment of Hard-to-Heal Wounds

Current standard wound care involves dressings that provide moisture and protection; however, dressings providing active healing are still scarce and expensive. We aimed to develop an ecologically sustainable 3D printed bioactive hydrogel-based topical wound dressing targeting healing of hard-to-heal wounds, such as chronic or burn wounds, which are low on exudate. To this end, we developed a form

Geosystem services from the subsurface : A literature review and a proposed set of indicators tailored to a Swedish setting

In this study, a literature review was conducted to identify indicators that can be utilised to assess and visualise the potential of the geophysical environment to deliver geosystem services. The literature review identified 24 studies and 22 technical reports, resulting in a list of 75 geosystem services indicators for 23 geosystem services associated with the subsurface. Building upon these fin

Design, integration and characterization of a Mach 5 axisymmetric contoured nozzle for the VKI-H3 hypersonic tunnel

In pursuit of advancing the capabilities of ground testing facilities, a complete road map for broadening operational range of the H3 hypersonic blowdown wind tunnel, operated at the von Karman Institute for Fluid Dynamics (VKI), with the addition of a new Mach 5 contoured nozzle is constructed. The main characteristics of the facility are presented. The supersonic ejector is identified as a criti

Effect of intermediate polarity molecule on phase transitions and bilayer structure in phospholipid membranes

Lipid-based formulations are widely utilized in various applications including food, cosmetics, and pharmaceuticals. The properties of these formulations can be influenced by changes in the external environment. As one example, dehydration can induce phase changes and alter the structural organization and molecular dynamic in the formulation, which potentially compromises the reversibility to a di

Multi modal time-resolved infrared and X-ray spectroscopic operando studies of the CO oxidation and NO reduction reactions on Rh(111)

We present an operando study where Ambient-Pressure X-ray Photoelectron Spectroscopy (AP-XPS), Polarization Modulation-InfraRed Reflection Absorption Spectroscopy (PM-IRRAS) and Mass Spectrometry (MS) were employed simultaneously with sub-minute time resolution to monitor the CO oxidation and NO reduction reactions on Rh(111). AP-XPS is a powerful tool to follow reactions at the surface-gas interf

Freeze-dried cake structural and physical heterogeneity in relation to freeze-drying cycle parameters

Freeze-drying is the preferred method to manufacture proteins in their solid state thus the understanding of the relationship between cycle parameters and cake properties remains of great interest. The present study aims to investigate the influence of the freezing conditions in the material properties at different layers throughout the dried structure, in the presence and absence of a protein. Pl

Iron insight : exploring dietary patterns and iron deficiency among teenage girls in Sweden

PURPOSE: This observational study examined the relationship between self-reported dietary patterns-omnivore, pescatarian, vegetarian, and vegan-and iron status among Swedish teenage girls. Additionally, we compared the consumption of various food groups in relation to iron status.METHODS: Data were collected from 475 female high school students in Malmö and Lund, Sweden, using questionnaires on di

Effects of ALS-associated 5'tiRNAGly-GCC on the transcriptomic and proteomic profile of primary neurons in vitro

tRNA-derived stress-induced RNAs (tiRNAs) are a new class of small non-coding RNA that have emerged as important regulators of cellular stress responses. tiRNAs are derived from specific tRNA cleavage by the stress-induced ribonuclease angiogenin (ANG). Loss-of-function mutations in the ANG gene are linked to amyotrophic lateral sclerosis (ALS), and elevated levels of specific tiRNAs were recently

Collaborative or Independent? : Buddhist Monks’ Perceptions of Nonconflict Between Religion and Science

Few studies have explored religious professionals’ interactions with scientific authority in work settings. Fewer still examine professionals outside Western contexts. We analyze the science-religion interface as it exists in Shaolin Temple—an ancient Chan Buddhist temple with a worldwide reputation for Shaolin Kungfu. Drawing on a near-exhaustive survey within Shaolin monastery and 23 interviews

Wealth and Marriage at the Cape: Consanguineous Unions as a Strategy

Marriage is among the most fundamental social relationships undergirding the transmission of cultural norms and family property. How marital partnerships are formed is of considerable interest to a broad range of social scientists, particularly when and whether partners are sought from within the family or from the outside. We study the relatively high levels of cousin marriage characteristic of E

COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms

We need to effectively combine the knowledge from surging literature with complex datasets to propose mechanistic models of SARS-CoV-2 infection, improving data interpretation and predicting key targets of intervention. Here, we describe a large-scale community effort to build an open access, interoperable and computable repository of COVID-19 molecular mechanisms. The COVID-19 Disease Map (C19DMa