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Theoretical rigor of customer experience scales : a systematic review and a roadmap for researchers

Purpose: Prior research has proposed a number of scales measuring the customer experience (CX), which tend to conceptualize and operationalize CX differently, raising potential confusion among researchers (e.g. regarding which scale to use). Addressing this issue, this article conducts a systematic review to inventorize key CX scales and assess their theoretical rigor, with a focus on the identifi

An ultra-short-period super-Earth with an extremely high density and an outer companion

We present the discovery and characterization of a new multi-planetary system around the Sun-like star K2-360 (EPIC 201595106). K2-360 was first identified in K2 photometry as the host of an ultra-short-period (USP) planet candidate with a period of 0.88 d. We obtained follow-up transit photometry, confirming the star as the host of the signal. High precision radial velocity measurements from HARP

Genome-wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors

Aggressive pituitary neuroendocrine tumors (PitNETs)/adenomas are characterized by progressive growth despite surgery and all standard medical therapies and radiotherapy. A subset will metastasize to the brain and/or distant locations and are termed metastatic PitNETs (pituitary carcinomas). Studies of potential prognostic markers have been limited due to the rarity of these tumors. A few recurren

Evaluation of a portable OSL/IRSL reader for radiation dose assessment of NaCl pellets – In situ individualised screening during R/N emergencies

Household salt, Sodium Chloride (NaCl), has been suggested as an appropriate material for retrospective and prospective optically stimulated luminescence (OSL) radiation dosimetry. The current paper investigates the potential application of NaCl pellets during a radiological and/or nuclear emergency, together with an existing portable reader, for application as a novel tool for in situ screening o

An exploratory study of teachers’ supportive communication during interactive book reading in the classroom

This study examines teachers’ use of evidence-based language learn­ing techniques in the classroom and possible impact on student ­engagement. Video recordings of nine primary school teachers conducting interactive book reading with their students were analyzed both according to the Communication Supporting Classroom Obser­vation Tool-Language Learning Interactions (CSCOT-LLI) and descriptively. QThis study examines teachers’ use of evidence-based language learn­ing techniques in the classroom and possible impact on student ­engagement. Video recordings of nine primary school teachers conducting interactive book reading with their students were analyzed both according to the Communication Supporting Classroom Obser­vation Tool-Language Learning Interactions (CSCOT-LLI) and descriptively. Q

DNA methylation in cord blood partially mediates the effects of prepregnancy BMI on early childhood offspring BMI

OBJECTIVE: We investigated whether prepregnancy BMI (prePregBMI) in women with obesity was associated with differential DNA methylation (DNAm) in cord blood (CB) and whether DNAm may mediate the association of prePregBMI and early childhood BMI z score (BMIz).METHODS: From the Treatment of Obese Pregnant Women (TOP) study, 232 mother-child pairs were included. We conducted an epigenome-wide associ

Impact of excess sugar on the whole genome DNA methylation pattern in human sperm

AIMS, PATIENTS & METHODS: Dietary factors may regulate the epigenome. We aimed to explore whether a diet intervention, including excess sugar, affects the methylome in human sperm, and to describe the sperm methylome. We used Whole Genome Bisulfite Sequencing (WGBS) to analyze DNA methylation in sperm taken at three time points from 15 males during a diet intervention; i) at baseline, ii) afte

Closing the loop without reinventing the wheel : public procurement for innovation promoting a circular economy

This theoretical paper adopts a procedural perspective to identify the challenges associated with the implementation of the full scope of approaches to circular public procurement (CPP). We contend that beyond considering CPP from a substantive standpoint (i.e. the procurement affects outside of the organization), adopting a procedural perspective (i.e. the procurement affects inside an organizati

A current view on the phenotypic antibiotic resistance of leading pathogens in wounded patients during the war in Ukraine

Background and aim: The purpose of this study was to determine the effectiveness of antibacterial drugs through cluster analysis of antibiotic sensitivity data from clinical isolates of Acinetobacter and Pseudomonas spp., obtained from soft tissue wounds and burn injuries. Methods: The cohort included 76 clinical isolates of Acinetobacter and Pseudomonas spp. obtained from 141 patients (male – 95,

Assessing the impact of global carbon dioxide changes on atmospheric fluctuations in Iran through satellite data analysis

Atmospheric Carbon Dioxide (CO2), a significant greenhouse gas, drives climate change, influencing temperature, rainfall, and the hydrologic cycle. This alters precipitation patterns, intensifies storms, and changes drought frequency and timing of floods, impacting ecosystems, agri-culture, water resources, and societies globally. Understanding how global CO2 fluctuations impact regional atmospher

Orbital analysis of stars in the nuclear stellar disc of the Milky Way

Context. While orbital analysis studies were so far mainly focused on the Galactic halo, it is possible now to do these studies in the heavily obscured region close to the Galactic Centre. Aims. We aim to do a detailed orbital analysis of stars located in the nuclear stellar disc (NSD) of the Milky Way allowing us to trace the dynamical history of this structure. Methods. We integrated orbits of t

Optimizing rare disorder trials: a phase 1a/1b randomized study of KL1333 in adults with mitochondrial disease

Over the past two decades there has been increased interest in orphan drug development for rare diseases. However, hurdles to clinical trial design for these disorders remain. This phase 1a/1b study addressed several challenges, while evaluating the safety and tolerability of the novel oral molecule KL1333 in healthy volunteers and subjects with primary mitochondrial disease.KL1333 aims to normali

Managing Soil Carbon Sequestration : Assessing the Effects of Intermediate Crops, Crop Residue Removal, and Digestate Application on Swedish Arable Land

Promoting the bioeconomy to aid in the achievement of sustainability goals has increased demand for biomass as feedstock. Residual biomass from agricultural production is an attractive option, as it is a by-product that does not compete with food production. However, crop residues are important for the preservation of soil quality, especially for the maintenance of soil organic carbon. Therefore,

Computing the Lipschitz Constant Needed for Fast Scene Recovery from CASSI Measurements

The linear inverse problem associated with the standard model for hyperspectral image recovery from CASSI measurements is considered. This is formulated as the minimization of an objective function which is the sum of a total variation regularizer and a least squares loss function. Standard first-order iterative minimization algorithms, such as ISTA, FISTA and TwIST, require as input the value of

The complexity of needs and roles of family members during breast cancer rehabilitation : a qualitative study

Background: Family members play a crucial role in supporting women with breast cancer during their recovery. In the complex situation of being an informal caregiver, their own health and ability to support the patient needs to be acknowledged. The aim was to explore the experiences, needs and roles of family members throughout the rehabilitation process of women with breast cancer. Methods: A qual

Five biomarkers from one cerebrospinal fluid sample to stage Alzheimer’s disease

Staging Alzheimer’s disease on the basis of the disease’s biological underpinnings might help with stratification and prognostication, both in the clinical setting and in clinical trials. We propose a staging model based on only five biomarkers, which are related to amyloid-β and tau pathologies in different ways and can be measured with a single sample of cerebrospinal fluid.

Omission of Radiotherapy in Primary Mediastinal B-Cell Lymphoma: IELSG37 Trial Results

PURPOSE The role of consolidation radiotherapy in patients with primary mediastinal B-cell lymphoma (PMBCL) is controversial. METHODS The IELSG37 trial, a randomized noninferiority study, aimed to assess whether irradiation can be omitted in patients with PMBCL with complete metabolic response (CMR) after induction immunochemotherapy. The primary end point was progression-free survival (PFS) at 30

Effect of nanoparticle concentration and surfactants on nanofluid pool boiling

Silica nanofluids are prepared with a concentration varying from 0.001 vol.% to 0.003 vol.%, and pool boiling of the nanofluids is experimentally investigated. It is found that critical heat flux and heat transfer coefficient increase by a maximum of 62.66% and 45.88% compared with deionized water. The best boiling performance is achieved with the nanofluid of 0.002 vol.%. In addition, the paper f

On the Separability of Functions and Games

We study the notion of (additive) separability of a function of several variables with respect to a hypergraph (H-graph). We prove the existence of a unique minimal H-graph with respect to which a function is separable and show that the corresponding minimal decomposition of the function can be obtained through a recursive algorithm. We then focus on (strategic form) games and propose a concept of