This book examines how dukeship – the position of being a duke – was defined and negotiated in Sweden between the late 1550s and the early 1620s. The aim is to shed light on how the structural problem of royal spares, with dukes as pillars and perils of hereditary monarchy, influenced politics and the integration process of a ruling house. Through an institutional biography approach and a critical

In a previous issue of Scandia (2019:2), historian Liesbeth Geevers argued that “new dynastic history” has emerged as a field within the discipline of history. This article elaborates on some of her suggestions discussing the fraternal conflicts in Sweden in the 1560s from the perspectives of dynastic centralisation and “the problem of the spare”. The conflicts between Erik XIV and his brothers, D

This article deals with the image-making of Swedish monarchs in the decades preceding and succeeding the Swedish Revolutionary Year of 1809, a year witnessing the dethronement of a king and the composition of a new constitution. In this era, the monarchies of Europe faced a great challenge in accommodating conflicting ideals of the Ancien Régime and of emergent bourgeois civic society. In dynastic

Byggnaders energibehov behöver minska i kombination med att energiförsörjningen (el, värme, gas, med mera) behöver fasa ut an­vändandet av fossila bränslen för att motverka den pågående kli­matförändringen. Olika strategier kan tillämpas för att utforma och bygga/renovera energieffektiva byggnader. En viktig åtgärd, oavsett strategi, är att minska energibehovet, vilket i Sverige vanligtvis inne­fa

Inom kort ska alla byggnader som uppförs inom EU vara nära-noll-energibyggnader. Det kräver förändring av den rådande byggnads-marknadens strukturer. CRAVEzero fokuserar på beprövade och nya metoder för att minska kostnaderna för nära-nollenergibyggnader i alla livscykelstadier genom att identifiera och eliminera de extra kostnaderna som är relaterade till processer, teknik och byggnadsdrift.

In March 2023, the Swedish national Board of Housing, Building and Planning (Boverket) published a proposal for new ventilation rates in Sweden. The supply air should by this be calculated based on an equation using the heated floor area as the main input. It is set as optional to use less ventilation flow if this could be sufficient. However, in a questionnaire to Swedish practitioners within the

Protein denaturation and aggregation resulting from the effects of interfacial stress that can be enhanced by flow and shear stress pose significant challenges in the production of therapeutic proteins such as monoclonal antibodies. The influence of flow on protein stability is closely intertwined with interfacial effects. In this study, we have developed a microfluidic device capable of exposing

A study of the performance of five commercial radiotherapy treatment planning systems ( TPSs) for common treatment sites regarding their ability to model heterogeneities and scattered photons has been performed. The comparison was based on CT information for prostate, head and neck, breast and lung cancer cases. The TPSs were installed locally at different institutions and commissioned for clinica

The matter of this work was to evaluate possibilities of biospecific immobilization of synthetic mannan-penicillin G acylase neoglycoconjugate on Concanavalin A support. The conjugate containing 37% (w/w) of yeast mannan was prepared. Significant biospecific interaction of this neoglycoenzyme with Con A was confirmed by precipitation method. The biospecific sorption of conjugate was investigated u

Eliminating the risk for ABO-incompatible transfusion errors and simplifying logistics by creating a universal blood inventory is a challenging idea. Goldstein and co-workers pioneered the field of enzymatic conversion of blood group A and B red blood cells (RBCs) to O (ECO). Using alpha-galactosidase from coffee beans to produce B-ECO RBCs, proof of principle for this revolutionary concept was ac

Although multiple system atrophy (MSA) is a neurodegenerative disorder leading to progressive disability and decreased life expectancy, little is known about patients' own evaluation of their illness and factors associated with poor health-related quality of life (Hr-QoL). We, therefore, assessed Hr-QoL and its determinants in MSA. The following scales were applied to 115 patients in the European

Nitrous oxide and isoflurane have different effects on absolute cerebral blood flow (CBF) and regional distribution of CBF in humans. In this study we examined the effects of isoflurane in combination with nitrous oxide on CBF. We studied 10 patients (two groups of five patients, ASA I) anaesthetized with 50% nitrous oxide and either 0.5 or 1.0 MAC of isoflurane during normocapnia (PaCO2 5.7 kPa)

The presented "spot-on-a-chip" technology enables easy enrichment of samples in the low nanomolar (1-5 nM) range and provides a fast and reliable automated sample preparation method for performing matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis with high sensitivity and throughput. Through microdispensing, which allows accurate deposition of 60-

Multiple and variable tyrosine sulfation in extracellular class II leucine-rich repeat proteins/proteoglycans were characterized by mass spectrometry. The sulfogroup on tyrosine is labile and is released from peptides under normal mass spectrometric conditions. Thus, special approaches must be considered in order to identify this modification. By using a combination of mass spectrometry studies op