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Tamoxifen response in primary breast cancer with special reference to tumour-specific VEGF-A and VEGFR2

Popular Abstract in Swedish I Sverige insjuknar årligen drygt 6000 kvinnor i bröstcancer. Antalet nyinsjuknade kvinnor i sjukdomen stiger något för varje år samtidigt som dödligheten minskar. En av orsaken till den minskade dödligheten är modern medicinsk behandling som idag kompletterar den kirurgiska behandlingen. Sjukdomsförloppet vid bröstcancer är mycket varierande beroende på tumörens utbredBackground: Treatment of primary breast cancer is individualised and adjuvant systemic treatment is delivered to most patients after surgery. Oestrogen receptor (ER) status and progesterone receptor status (PR) can define patients who would benefit from adjuvant endocrine therapy with tamoxifen (TAM) alone or as chemo-endocrine therapy. In spite of adjuvant treatment with TAM, some patients with h

Capabilities of Convolutional Codes: Unequal Error Protection and More

Many communication systems obtain enhanced performance by using concatenated coding schemes. Turbo codes and woven convolutional codes are two examples of such schemes. The component codes used in these schemes operate at rates close to or even above capacity where the free distance of a code is not relevant anymore and other distance properties have to be taken into account. This thesis consists

Scanning angles for directional pointing

The present study was performed in order to get a better understanding of the influence of the scanning angle interval on navigation performance, gestures and strategies in a more realistic outdoor setting. Results indicate that users are able to handle a wide range of angle intervals. We observe different gestures and strategies and provide recommendations for suitable angle intervals. Our observ

Aqueous Block Copolymer Systems. Self-association, Phase Behaviour and Partitioning of Biomolecules

The phase and partitioning behaviour of aqueous block copolymer systems has been studied. The block copolymers used in this work were built up of three blocks. The middle block was poly(propylene oxide) (PPO) and hydrophobic. The two outer blocks constisted of poly(ethylene oxide) (PEO) chains and less hydrophobic. The amphiphilic property of this PEO-PPO-PEO block copolymers enable self-associati