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Functional role of central muscarinic receptors for micturition in normal conscious rats

Purpose: Antimuscarinic agents, which are used in to treat urgency and urge incontinence, have well-known effects on peripheral muscarinic receptors. However, some currently used drugs may have effects on muscarinic receptors in the brain and/or spinal cord involved in voiding control. We tested if muscarinic receptors within the central nervous system mediate a tonic excitatory influence on voidi

The five-year incidence of blindness after introducing a screening programme for early detection of treatable diabetic retinopathy

The incidence of moderate visual impairment and blindness due to diabetic retinopathy was studied 5 years after introducing a screening system for early detection of treatable retinopathy. Photocoagulation was performed in patients with clinically significant macular oedema, severe preproliferative, and proliferative retinopathy. Eighty-eight percent of 470 Type 1 and 88% of 388 Type 2 diabetic pa

Sustainability concept for a newly built urban area in Malmo, Sweden

National goals regarding sustainable development from the Swedish government were decisive in the planning process when the newly built city district Western Harbour was established in the city of Malmo, Sweden. A systems analysis was used as a tool for evaluating different collection and treatment systems. This type of analysis does not include more subjective factors such as acceptance of organi

The defeasible nature of coherentist justification

The impossibility results of Bovens and Hartmann (2003, Bayesian epistemology. Oxford: Clarendon Press) and Olsson (2005, Against coherence: Truth, probability and justification. Oxford: Oxford University Press.) show that the link between coherence and probability is not as strong as some have supposed. This paper is an attempt to bring out a way in which coherence reasoning nevertheless can be j

Through-drying of tissue at high intensities - An experimental study

Experimental data for through-drying of tissue at intensities comparable to industrial conditions arc presented. The study covers three basis weights, 20, 30 and 40 g/m(2), dried at drying air temperatures of 100, 150 and 200 degrees C. Unlike most experimental data on through-drying in the literature, the experiments in this study were performed under conditions of constant pressure drop across t

Globaliseringsrörelsen – en ny social rörelse eller en klassisk konfliktdimension i nytt sammanhang?

Allt sedan demonstrationerna mot WTO i Seattle har den globala rättviserörelsen uppmärksammats för att den har sammanfört aktivister från disparata rörelsemiljöer, i gemensamma protester mot den ekonomiska globaliseringens effekter och de globala organ som anses driva fram denna utveckling. I denna artikel diskuteras hur dessa mobiliseringar kan förstås utifrån gängse teorier om "nya sociala rörel

Decays of eta and eta ' and what can we learn from them?

A short overview of eta and eta' decays is given with an emphasis on what can be learned for the strong interaction from them. The talk consists of a short introduction to Chiral Perturbation Theory, a discussion of eta -> 3 pi beyond p(4) and some of the physics involved in eta' -> eta pi pi, 3 pi as well as an overview of anomalous processes.

Intrapatient evolution of HIV-1 in the context of coreceptor usage

The variable region 1 to 3 (V1-V3) of the HIV-1 envelope plays an important role in coreceptor usage. Early in infection HIV- 1 is using CCR5 as coreceptor to enter target cells (R5 viruses) whereas viruses using CXCR4 as coreceptor (X4 viruses) may appear later in infection. This broadening or switch in coreceptor usage is associated with progression to AIDS. In my thesis work, we have compared t

Time and wavelength resolved spectroscopy of turbid media using light continuum generated in a crystal fiber

We report a novel system for time-resolved diffuse remission spectral measurements, based on short light continuum pulses generated in an index-guided crystal fiber, and a spectrometer-equipped streak camera. The system enables spectral recordings of absorption and reduced scattering coefficients of turbid media in the wavelength range 500 - 1200 nm with a spectral resolution of 5 nm and a tempora

Implementing Java Compilers Using ReRAGs

Rewritable Reference Attributed Grammars (ReRAGs) is a recently developed compiler-compiler technology based on object-orientation, aspect-orientation, reference attributed grammars, and conditional rewrites. In this paper we describe our experiences from using ReRAGs for implementing Java compilers. We illustrate how the usage of ReRAGs renders a rather compact, yet easy-to-understand and modular

Computational study of the combustion process and NO formation in a small-scale wood pellet furnace

This paper presents a computational study of the combustion process of wood pellets in a small-scale grate fired furnace. The objectives were to obtain detailed information on the combustion characteristics and NO formation in the furnace, and to examine the effect of secondary air on the combustion process. The simulation results were compared with experimental data in terms of flame temperature

Making States Comply : The European Commission, the European Court of Justice, and the Enforcement of the Internal Market

One of the central bones of contention in the study of the European Union (EU) is the capacity of its supranational institutions to be a driving force in the process toward deeper integration. Whereas existing research predominantly addresses the institutions’ ability to shape European integration through pre-decisional agenda-setting, this study examines the scope for supranational influence in t

Modelling the effect of function and disease activity on costs and quality of life in rheumatoid arthritis

Objective. When treatments with the potential to change the natural history of a disease are introduced, their longer-term effect on costs and quality of life (utility) has to be estimated using economic models. However, to remain useful tools, models must be updated when new information becomes available. Our earlier models in rheumatoid arthritis (RA) have been based on functional status, but it