The rapidly growing collection of diverse genome-scale data from multiple tumor types sheds light on various aspects of the underlying tumor biology. With the objective to identify genes of importance for breast tumorigenesis in men and to enable comparisons with genes important for breast cancer development in women, we applied the computational framework COpy Number and EXpression In Cancer (CON

We examine the role of regional import flows for renewal of regional industries. The hypothesis is that imports stimulate renewal of local industries by being vehicles for technology diffusion and means by which local firms can exploit advantages of global specialisation. We find robust and positive relationships between high-quality imports and renewal of regional exports, where the latter are me

Background: There is limited information about any association between the onset of atrial fibrillation (AF) and the presence of valvular disease. Methods: We retrospectively examined 940 patients in sinus rhythm, examined by echocardiography in 1996. During 11 years of follow-up, we assessed the incidence of AF and outcome defined as valvular surgery or death, in relation to baseline valvular fun

Miller R, D'Agostino D, Erlanson-Albertsson C, Lowe ME. Enterostatin deficiency increases serum cholesterol but does not influence growth and food intake in mice. Am J Physiol Endocrinol Metab 297: E856-E865, 2009. First published July 21, 2009; doi:10.1152/ajpendo.91008.2008.-A pentapeptide released from procolipase, enterostatin, selectively attenuates dietary fat intake when administered periph

Alcohol use has been shown to interfere with treatment for depression, but consumption habits are not routinely screened in primary care. To date, few studies have compared the alcohol consumption habits of patients with depression to the general population. The purpose of this study was to compare alcohol habits in adults diagnosed with depression in primary care to the general adult population i

There is a lack of validated autism-specific outcome measures for large-scale evaluation of the effectiveness of psycho-educational programmes. To fill this gap the Environment Rating Scale (ERS) was adapted from an interview version to a staff-completed questionnaire version (ERS-Q). The ERS-Q was tested regarding data quality, validity, reliability and ease of understanding amongst 18 residentia

A physical inactive lifestyle is associated with increased prevalence of chronic diseases such as cardiovascular disease, type 2 diabetes, osteoporosis and cancer. The proportion of pregnant women with overweight or obesity is increasing rapidly across the world and this excess weight, mainly obesity, is associated with increased risk of health problems during pregnancy and in connection with chil

Ethnography has become something of a buzzword in recent years. It is talked about and invoked in disciplines ranging from anthropology and ethnology to literature, history, business administration and design studies. Textbooks that teach ethnography tend to imbue students with the impression that ethnography is a mode of systematic investigation by which the researcher gets closer to the realitie

This report addresses the related problems of trajectory generation and time-optimal path tracking with online obstacle avoidance. We consider the class of four-wheeled vehicles with independent steering and driving on each wheel, also referred to as pseudo-omnidirectional vehicles. Appropriate approximations of the dynamic model enable a convex reformulation of the path-tracking problem. Using th

Urban water scarcity is increasingly seen as a governance issue, not least in cities like Hyderabad, India, where the demand for urban water exceeds the available supply to the extent that some low priority areas in the city receive water for only a few hours on alternate days. Based on a multi-level perspective in transition studies, this study explores the major interplay between actors in the u

A major concern in common disease epigenomics is distinguishing causal from consequential epigenetic variation. One means of addressing this issue is to identify the temporal origins of epigenetic variants via longitudinal analyses. However, prospective birth-cohort studies are expensive and time consuming. Here, we report DNA methylomics of archived Guthrie cards for the retrospective longitudina

Laminar burning velocities, S-L, of methyl formate and air flames were determined at atmospheric pressure and initial gas temperatures, T, of 298, 318, 338 and 348 K. Measurements were performed in non-stretched flames, stabilized on a perforated plate burner at adiabatic conditions, generated using the heat flux method. These new experimental data shed light on discrepancies seen in previously pu

Detta är en pilotstudie som problematiserar vindkraftens regelverk i Sverige utifrån ett rättssociologiskt och planeringsjuridiskt perspektiv. Under hösten 2008 kom ett betänkande från miljöprocessutredningen gällande en effektivisering av prövning av vindkraft (SOU 2008:86). Bakgrunden var att krav på att en snabbare och enklare process från projektering till uppförande av vindkraftverk hade rest

Abstract in UndeterminedWe found that a large Swedish grocery retailer was missing a structured approach for deciding on contract type when procuring trucking services in shipper-forwarder relationships. In this context, we identified four contract types: dedicated services, periodical services, truckload services, and less-than-truckload services. From previous literature, we found that trucking